Articles, Health & Wellness

CBD for Pain: How It Works, Research, & More

CBD for Pain: What You Should Know

Due to its skyrocketing popularity, more and more people are trying CBD for pain. How does it work though, and does it actually work? Find out in our latest guide.


researcher once referred to pain as “the oldest medical problem.” Some of the earliest doctors actually valued pain, touting pain as part of the healing process, or a divine reminder that people were living. However, a shift took place and it became a positive thing to relieve pain.

From opium and sedating chloroform, historical physicians tried a lot of questionable agents in an effort to help people feel better. But it wasn’t until the last several decades that doctors started to really understand the physiology of pain, where it comes from, and potentially the best ways of managing it.

Since hemp-based CBD became legal in 2018, the cannabinoid has gained widespread popularity, and for good reason. About 4 of 10 people who take CBD do so for pain relief, but what is CBD and how does it work? Most importantly, does CBD for pain actually work?

In this article, we’ll explore this important topic in-depth!

What is CBD and How Does It Work

What is CBD and How Does It Work?

In short, CBD (cannabidiol) is just one of the more than 100 cannabinoids found in plants that come from the Cannabis Sativa family, which includes hemp. In fact, CBD is one of the most concentrated cannabinoids in the hemp plant, even though others like THC (tetrahydrocannabinol) and CBG (cannabigerol) are present. Cannabinoids, scientifically referred to as phytocannabinoids, are highly similar in nature to something produced by our own bodies: endocannabinoids.

Endocannabinoids interact with a series of widespread receptors throughout the body, primarily in the brain, but also in the immune system, central nervous system, and peripheral nervous system. This series of receptors is known as the endocannabinoid system (ECS). CBD seems to act as a balancing molecule within the ECS; instead of having a specific affinity to certain receptors like THC, the cannabinoid stabilizes the body’s own endocannabinoids and possibly signals the body to produce more. The ECS plays a role in a long list of physiological processes, including things like inflammation, pain perception, and stress.

Can CBD Actually Help Pain? Here’s What We Know

Throughout history, researchers have examined cannabis for its potential pain-relieving qualities. However, obstacles came along with THC having intoxicating or sedating effects. With the ability to isolate other cannabinoids like CBD, researchers found that CBD could potentially be used for therapeutic pain relief without dealing with the negative effects of THC.

CBD oil may work for pain for a number of reasons. With knowing how the cannabinoid works in the ECS, it is easy to see that CBD could target different types of pain, such as general soreness, chronic pain, or even pain caused by inflammation. Pain can stem from a number of problems, such as free radical accumulation, tissue damage, oxidative stress, and more. Let’s take a look at the specifics behind different pain types and why CBD may help.

Inflammatory Pain

CBD for Inflammatory Pain

Inflammation is one of the bigger culprits behind pain, so targeting inflammation and inflammatory responses with CBD may help to alleviate a number of types of pain. For example, headaches, toothaches, and earaches are all caused by some form of inflammation. CBD seems to suppress inflammation, so it may do a lot of good to help with specific types of inflammatory pain.

Chronic Pain

CBD for Chronic Pain

CBD oil for chronic pain may help for a few reasons. For one, CBD has been shown to reduce levels of glutamate in the spinal cord in animal studies. Glutamate can actually cause an increase in pain signal transmissions. Secondly, CBD may also increase the signaling of a molecule known as anandamide and sometimes call by the name the “bliss molecule.” Enhanced anandamide levels may help encourage feelings of general happiness, which can be an issue for chronic pain sufferers.

Neuropathic Pain

CBD for Neuropathic Pain

Even though neuropathic pain is a highly targeted area of research where CBD is concerned, the research is only just getting started. What we do know is CBD does seem to have effectiveness for neuropathic pain that is related to things like multiple sclerosis. The mechanisms by which this is possible may be related to the cannabinoid’s ability to suppress inflammatory responses and possibly act as an analgesic.

Muscle Pain and Soreness

CBD for Muscle Pain and Soreness

A number of active people use CBD for pain related to muscle soreness and stiffness. When you are really feeling the “burn” after a hard day at the gym, CBD may help to improve muscle recovery times. CBD has antioxidant properties, which can help prevent free radical accumulation that may be associated with heightened muscle soreness. Plus, the tiny tears in muscles brought about by intense activity can lead to inflammation, which may also be helped with CBD.

Different Ways to Use CBD for Pain

Due to its wide range of natural properties, CBD has quickly become one of the most preferred ways to help alleviate pain naturally.

In addition, and perhaps another factor leading to the cannabinoid’s rise in popularity, CBD can be used in a variety of easy ways.

Here are just a few of the most common ways to use CBD for pain:

CBD for Pain: How Long Does It Take to Work?

Research suggests the CBD oil can get to work more quickly when taken sublingually; possibly in as little as 15 minutes. Simply swallowing the CBD oil can lead to a longer onset of effects because the oil has to work its way through the digestion process before it gets to work. Beyond those general guidelines, however, each person can have a unique experience. A number of factors can affect how long it takes for CBD to work for pain, such as:

  • The type of CBD oil you are taking (such as broad-spectrum, full-spectrum, or isolate)
  • The potency of the CBD oil you are taking (a higher potency may mean a faster onset of effects)
  • The user’s individual body chemistry (height, weight, chemical makeup, etc.)
  • The type and level of pain the user is experiencing

Get Started with fabuleaf™ Full Spectrum CBD Products

fabuleaf full spectrum CBD products

If you’re curious about using CBD oil for pain, you’ve come to the right place. At fabuleaf, we offer a wide selection of premium-grade, full spectrum CBD products including creams, softgels, and oils! All fabuleaf products are produced from hemp that is grown organically and hand-harvested by our bioscience team who boast over 30 years of experience in seed genetics. With complete “seed to shelf” control over our entire supply chain, our team is able to consistently produce products that are high-quality, safe, and effective.

Whether your considering trying using CBD for the first time or looking for a new product to add to your health regime, fabuleaf™ offers the quality you deserve!

Try any of our top-rated hemp CBD products and experience the fabuleaf™ difference.


Thanks for reading our latest guide. If you have any questions, comments, or, perhaps even an experience you’d like to share, drop us a message in the comments and we’ll be sure to get back to you!


The information contained in this article is not intended to serve as a substitute for advice or guidance from a certified doctor or health professional. Before trying Cannabidiol (CBD) or purchasing any CBD product, you should always conduct your own research and consult with your doctor. While Cannabidiol (CBD) is classified as “generally well tolerated with a good safely profile” by the World Health Organization (WHO), more research is needed in order to fully evaluate the safety and effectiveness of CBD on a personalized basis.

fabuleaf™ products have not been evaluated by the Food and Drug Administration (FDA) and are not intended to diagnose, treat, cure, or prevent any disease.